Tentang kami:
A peptide is a chain of amino acids linked by peptide bonds. Peptides are mainly involved in protein regulation, angiogenesis, cell proliferation, melanogenesis, cell migration, and inflammation. Bioactive peptides have been widely used in the cosmetic industry in recent decades. Peptides require low molecular weight (> 500 Da), in order to reduce the diffusion of the peptide between the epidermal layers, high stability and solubility. Over the years, the scientific community has developed a small and stable synthetic peptide fragment that activates collagen production and reduces facial wrinkles and pigmentation. Trifluoroacetyl tripeptide-2 (sequence: TFA-Val-Try-Val-OH) tripeptide synthesis, designed as a matrix metalloproteinase and elastase inhibitor. In vitro studies on the protection of ECM by trifluoro-acetyl tripeptide 2(TT2), the synthesis of proteoglycan in cell-matrix interactions, and the effect on progerin synthesis in mature human normal fibroblasts have been recently identified as a co-inducer of cellular senescence. The results suggest that trifluoroacetyl tripeptide 2 has a broader range of anti-aging properties. This reduces progerin synthesis, increases proteoglycan production, and shrinks collagen, thereby reducing wrinkles and improving tissue stiffness. In addition, its anti-wrinkling, anti-flow hanging and skin tightening effects were evaluated in two in vitro split face studies. Trifluoroacetyl tripeptide 2 has been shown to have progressive effects on wrinkles, tightness, elasticity, and sagging.
Bisakah penuaan trifluoroacetyl tripeptide-2?
Studi telah menunjukkan bahwa penuaan sel terkait erat dengan progerin. Dengan penuaan, presenilin menumpuk lebih banyak dan lebih banyak di dalam tubuh, yang menyebabkan cacat nuklir dan kerusakan DNA, yang mengarah ke berbagai penuaan kulit. Trifluoroacetyl tripeptide-2 adalah tripeptida aktif elafin, turunan dari elastase inhibitor. Ini mengurangi sintesis progerin dan meningkatkan kelemahan kulit, kendur dan kerutan.
Mekanisme
1. Menghambat sintesis progerin untuk menunda penuaan seluler.
2. Mempromosikan produksi sindecan dan memperpanjang kehidupan sel.
3. Menghambat aktivitas matriks metalloproteinases MMP1, MMP3 dan MMP9, mengurangi kerusakan protein matriks ekstraseluler dan mempertahankan integritasnya.
4. Menghambat aktivitas elastase, mengurangi degradasi elastin, dan membuat kulit lebih kencang dan lebih elastis.
Aplikasi
Ini cocok untuk semua jenis anti-kerut dan anti-penuaan, perbaikan pengencangan, anti-photoaging, perawatan tubuh pasca-kelahiran dan pasca-sun, dll. Ditambahkan pada tahap akhir produksi kosmetik
Waktu posting: 2025-07-02